The Anti-Mouse Fc epsilon Receptor I alpha (FceR1) FITC Antibody from MyBioSource.com is a Hamster Monoclonal antibody. This antibody recognizes Mouse antigen. The Anti-Mouse Fc epsilon Receptor I alpha (FceR1) FITC Antibody has been validated for the following applications: Flow Cytometry.
Description
The Mar-1 monoclonal antibody binds to the Fc epsilon Receptor I alpha subunit (FceR1a), which is a transmembrane glycoprotein from the immunoglobulin superfamily. FceR1a lacks signal-transducing ability and is expressed by mast and basophil cells.
The Fc epsilon Receptor I alpha subunit is upregulated by IgE and forms a tetramer with a beta subunit and two gamma subunits, which have ITAM (immunoreceptor tyrosine-based activation motifs). The complex formed by the four subunits has very important roles in the IgE-facilitated allergic reactions